Title: The first complete papillomavirus genome characterized from a marsupial host: a novel isolate from Bettongia penicillata
Authors: Bennett, Mark D ×
Reiss, Andrea
Stevens, Hans
Heylen, Elisabeth
Van Ranst, Marc
Wayne, Adrian
Slaven, Michael
Mills, Jennifer N
Warren, Kristin S
O'Hara, Amanda J
Nicholls, Philip K #
Issue Date: May-2010
Publisher: American Society for Microbiology (ASM)
Series Title: Journal of Virology vol:84 issue:10 pages:5448-53
Abstract: The first fully sequenced papillomavirus (PV) of marsupials, tentatively named Bettongia penicillata papillomavirus type 1 (BpPV1), was detected in papillomas from a woylie (Bettongia penicillata ogilbyi). The circular, double-stranded DNA genome contains 7,737 bp and encodes 7 open reading frames (ORFs), E6, E7, E1, E2, E4, L2, and L1, in typical PV conformation. BpPV1 is a close-to-root PV with L1 and L2 ORFs most similar to European hedgehog PV and bandicoot papillomatosis carcinomatosis virus types 1 and 2 (BPCV1 and -2). It appears that the BPCVs arose by recombination between an ancient PV and an ancient polyomavirus more than 10 million years ago.
ISSN: 0022-538X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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