Imaging tutorial: differential diagnosis of bright lesions on diffusion-weighted MR images
Stadnik, Tadeusz W × Demaerel, Philippe Luypaert, Robert R Chaskis, Christo Van Rompaey, Katrijn L Michotte, Alex Osteaux, Michel J #
Radiological Society of North America
Radiographics vol:23 issue:1 pages:e7
High sensitivity (94%) and specificity (100%) have been reported in the diagnosis of acute cerebral infarction with diffusion-weighted magnetic resonance (MR) imaging. However, high signal intensity on diffusion-weighted MR images and low apparent diffusion coefficient values (similar to the findings in acute cerebral infarction) were reported in such diverse conditions as hemorrhage, abscess, lymphoma, and even Creutzfeldt-Jakob disease. The differential diagnosis of these conditions (eg, acute ischemic infarction and acute cerebral hemorrhage) is critical for the determination of appropriate treatment. The authors present a systematic review of bright lesions on diffusion-weighted MR images and their differential diagnosis, with emphasis on the practical and clinical approaches of differential diagnosis.