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Title: Spontaneous healing of Langerhans cell histiocytosis (histiocytosis X)
Authors: Corbeel, Lucien ×
Eggermont, Ephrem
Desmyter, Jan
Surmont, I
De Vos, Rita
Peeters, C
Cobbaert, C
Eykens, A #
Issue Date: Oct-1988
Series Title: European Journal of Pediatrics vol:148 issue:1 pages:32-3
Abstract: A 3-month-old male infant presented with pallor, hepatomegaly (4.5 cm), splenomegaly (1.5 cm), anaemia (Hb 6 g/dl) and thrombocytopenia (16 X 10(9)/l). A liver biopsy was diagnostic for Langerhans cell histiocytosis (histiocytosis X). The patient's lymphocytes, co-cultured with neonatal lymphocytes, were positive for virus-like particles without reverse transcriptase activity. The hepatomegaly diminished after 6 months and a second liver biopsy showed decreased histiocytic infiltration. A second viral blood culture remained negative. After 14 months, the hepatomegaly had disappeared completely and there were no more abnormal haematological or clinical findings.
ISSN: 0340-6199
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Medicine - miscellaneous
Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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