In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression
Carlin, Sean × Pugachev, Andrei Sun, Xiaorong Burke, Sean Claus, Filip O'Donoghue, Joseph Ling, C. Clifton Humm, John L #
Elsevier science inc
Nuclear medicine and biology vol:36 issue:7 pages:821-831
Purpose: To characterize a tumor model containing a hypoxia-inducible reporter gene and to demonstrate utility by comparison of reporter gene expression to the uptake and distribution of the hypoxia tracer F-18-fluoromisonidazole (F-18-FMISO).