Title: In vivo animal functional MRI: improved image quality with a body-adapted mold
Authors: Landuyt, Willy ×
Sunaert, Stefan
Farina, Davide
Meijerink, Martijn
Béatse, Eric
Van Hecke, Paul
Hermans, Robert
Marchal, Guy
Lambin, Philippe
Bosmans, Hilde #
Issue Date: Aug-2002
Series Title: Journal of magnetic resonance imaging : JMRI vol:16 issue:2 pages:224-7
Abstract: PURPOSE: To reduce functional magnetic resonance imaging (fMRI) susceptibility distortion at the air/tissue interphase in animal experiments. MATERIALS AND METHODS: We investigated the applicability of a body-adaptable flexible mold consisting of a fast-setting alginate. This technique was implemented for subcutaneous growing tumors in rats and for the brains of monkeys. RESULTS: The T(2)*-weighted gradient-echo, echo-planar imaging (GE-EPI) data obtained with the body-adapted mold showed a reduction of susceptibility artifacts and improved image quality. With both rat tumor and monkey brain, an optimized match with the anatomical T(1) images was possible. CONCLUSION: The present mold methodology is a rapid, easy, and inexpensive way to reduce magnetic susceptibility during animal GE-EPI.
ISSN: 1053-1807
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Translational MRI (+)
× corresponding author
# (joint) last author

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