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Title: Folding and stability of globular proteins and implications for function
Authors: Travaglini-Allocatelli, Carlo
Ivarsson, Ylva
Jemth, Per
Gianni, Stefano # ×
Issue Date: Feb-2009
Publisher: Current biology ltd
Series Title: Current Opinion in Structural Biology vol:19 pages:3-7
Abstract: The description of protein folding pathways and the principles that govern them has proven to be one of the most difficult problems to be solved in structural biology. But the combination of experiments and simulations has now provided a clearer picture of the chemistry involved. Once folded, however, proteins remain dynamic systems making possible both small-scale and large-scale structural and/or dynamical changes upon binding or releasing of ligands and during catalysis. In this review we focus on recent advances in the field of protein folding and discuss possible links between folding, stability, and binding dynamics.
URI: 
ISSN: 0959-440X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Signal Integration in Cell Fate Decision
× corresponding author
# (joint) last author

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