Title: Relatieve bijnierschorsinsufficiëntie bij leverlijden: het “hepatoadrenaal syndroom”?
Authors: Gielen, Evelien
Laleman, Wim
Verslype, Chris
Wilmer, Alexander
Nevens, Frederik # ×
Issue Date: 2009
Publisher: Nederlandstalige medische Faculteiten in België
Series Title: Tijdschrift voor Geneeskunde vol:65 issue:6 pages:226-230
Abstract: Relative adrenal insufficiency (RAI) signifies that the degree of the cortisol increase is not in proportion to the degree of inflammation and insufficient to maintain homeostasis in organ systems. Whether a treatment of RAI with corticosteroids decreases mortality, is still being debated.
RAI may also be observed in patients with liver failure and no evidence of sepsis, leading to the term "hepato-adrenal syndrome". Its prevalence varies from 33% in acute liver failure to 65% in chronic liver disease. RAI contributes to the haemodynamic instability and death of patients with liver disease and constitutes a possible indication for treatment. At the present time no sufficiently controlled data do exist to recommand the use of cortico- steroids in patients with liver failure.
Finally, a better definition of RAI in patients with advanced liver disease, is needed.
ISSN: 0371-683X
VABB publication type: VABB-1
Publication status: published
KU Leuven publication type: AT
Appears in Collections:Gerontology and Geriatrics
Laboratory for Clinical Infectious and Inflammatory Disorders
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.