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Title: Alkaline encrusted pyelitis
Authors: Van Hooland, S ×
Vandooren, A K
Lerut, Evelyne
Oyen, Raymond
Maes, B #
Issue Date: 2005
Series Title: Acta Clinica Belgica vol:60 issue:6 pages:369-72
Abstract: Alkaline encrusted pyelitis is an infectious disease characterised by encrustations in the wall of the upper urinary tract, surrounded by severe inflammation. Destruction of native kidneys and kidney grafts may occur, resulting in end stage renal failure. Corynebacterium group D2, an urea splitting microorganism, is nearly exclusively associated with this disease. The most important predisposing factors are previous urological procedures and an immunosuppressed state. In a suggestive clinical context, diagnosis should be made with unenhanced computed tomography findings and bacteriologic isolation of the responsible microorganism. The treatment is threefold: appropriate antibiotic therapy, by preference with glycopeptides, acidification of urine and chemolysis, and if needed, surgical removal of encrustations. We report the case of a patient who was diagnosed with this rare condition and could escape maintenance dialysis after correct diagnosis was made and conservative treatment was started using antibiotics and combined oral and local acidification.
ISSN: 1784-3286
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Translational Cell & Tissue Research
Laboratory of Nephrology
× corresponding author
# (joint) last author

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