Title: Diversity-Oriented Synthesis of Substutited Furo[2,3-b]pyrazines
Authors: Mehta Pravinchandra, Vaibhav
Modha, Sachinkumar
Ermolatev, Denis
Van Hecke, Kristof
Van Meervelt, Luc
Van der Eycken, Erik # ×
Issue Date: Jan-2009
Publisher: Csiro publishing
Series Title: Australian journal of chemistry vol:62 issue:1 pages:27-41
Abstract: A highly efficient method for the synthesis of diversely substituted furo[2,3-b] pyrazines has been elaborated. The Ag+- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)pyrazin-2(1H)-ones affords substituted furo[2,3-b] pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b] pyrazines.
ISSN: 0004-9425
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
Chemistry - miscellaneous
Biochemistry, Molecular and Structural Biology Section
× corresponding author
# (joint) last author

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