Radiotherapy and Oncology vol:68 issue:1 pages:69-74
Respiration-induced movement of the upper abdominal organs (pancreas, liver and kidneys) was assessed in 12 subjects using dynamic magnetic resonance imaging. The movement of each organ in the cranio-caudal, the lateral and the anterior-posterior direction was deduced from the movement of the center of gravity on two-dimensional images. This center of gravity was computed from the volume delineated on sequential 8-mm slices of both sagittal and coronal dynamic series. The largest movements were noticed in the cranio-caudal direction for pancreas and liver (23.7+/-15.9 mm and 24.4+/-16.4 mm). The kidneys showed smaller movements in the cranio-caudal direction (left kidney 16.9+/-6.7 mm and right kidney 16.1+/-7.9 mm). The movements of the different organs in the anterior-posterior and lateral directions were less pronounced. It is of the greatest importance to be aware of these movements in the planning of a conformal radiation treatment for pancreatic cancer.
Bussels B., Goethals L., Feron M., Bielen D., Dymarkowski S., Suetens P., Haustermans K., ''Respiration-induced movement of the upper abdominal organs : a pitfall for the three-dimensional conformal radiation treatment of pancreatic cancer'', Radiotherapy and oncology, vol. 68, pp. 69-74, 2003, Elsevier Science Ireland Ltd.