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Title: Computer-aided detection of colonic polyps using low-dose CT acquisitions
Authors: Kiss, Gabriel ×
Drisis, Stylianos
Bielen, Didier
Maes, Frederik
Van Cleynenbreugel, Johan
Marchal, Guy
Suetens, Paul #
Issue Date: Sep-2006
Publisher: Association of University Radiologists
Series Title: Academic Radiology vol:13 issue:9 pages:1062-1071
Abstract: RATIONALE AND OBJECTIVES: This report proposes an alternative method for the automatic detection of colonic polyps that is robust enough to be directly applicable on low-dose computed tomographic data. MATERIALS AND METHODS: The polyp modeling process takes into account both the gray-level appearance of polyps (intensity profiles) and their geometry (extended Gaussian images). Spherical harmonic decompositions are used for comparison purposes, allowing fast estimation of the similarity between a candidate and a set of previously computed models. Starting from the original raw data (acquired at 55 mA), five patient data sets (prone and supine scans) are reconstructed at different dose levels (to 5 mA) by using different kernel filters, slice overlaps, and increments. Additionally, the efficacy of applying an edge-preserving smoothing filter before detection is assessed. RESULTS: Although image quality decreases when decreasing acquisition milliamperes, all polyps greater than 6 mm are detected successfully, even at 15 mA. Although not important at high doses, smoothing improves detection results for ultra-low-dose (tube current<15 mA) data. CONCLUSION: The advantage of low-dose scans is a significant decrease in effective dose from 4.93 to 1.61 mSv while retaining high detection values, particularly important when thinking of population screening.
URI: 
ISSN: 1076-6332
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - PSI, Processing Speech and Images
Radiology
× corresponding author
# (joint) last author

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