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Title: Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: A randomized phase III trial of the European Osteosarcoma Intergroup
Authors: Lewis, Ian J ×
Nooij, Marianne A
Whelan, Jeremy
Sydes, Matthew R
Grimer, Robert
Hogendoorn, Pancras C. W
Memon, Muhammad A
Weeden, Simon
Uscinska, Barbara M
van Glabbeke, Martine
Kirkpatrick, Anne
Hauben, Esther
Craft, Alan W
Taminiau, Antonie H. M #
Issue Date: Jan-2007
Publisher: Oxford University Press
Series Title: Journal of the National Cancer Institute vol:99 issue:2 pages:112-128
Abstract: Background Previous randomized controlled trials that used the two-drug chemotherapy regimen of cisplatin and doxorubicin as the conventional arm showed no evidence of benefit from an increase in the number of agents or the length of treatment. It was then proposed that survival could be improved by increasing the planned dose intensity of cisplatin and doxorubicin.
URI: 
ISSN: 0027-8874
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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