Title: The value of magnetic resonance imaging in the diagnosis of residual or recurrent acquired cholesteatoma after canal wall-up tympanoplasty
Authors: Jeunen, Gert ×
Desloovere, Christian
Hermans, Robert
Vandecaveye, Vincent #
Issue Date: Jan-2008
Series Title: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology vol:29 issue:1 pages:16-8
Abstract: OBJECTIVE: The value of magnetic resonance imaging (MRI) in the diagnosis of recurrent or residual cholesteatoma after canal wall-up tympanoplasty is studied in a retrospective cohort study at a tertiary referral center. PATIENTS: A total of 31 patients, who underwent 32 canal wall-up tympanoplasty procedures with MRI before revision surgery, were included in the study. INTERVENTIONS: MRI examination, using both the conventional and echo-planar diffusion-weighted sequences, was performed, with additional spin echo diffusion-weighted MRI sequences in 4 patients. All patients were treated with a canal wall-up tympanoplasty. MAIN OUTCOME MEASURES: The presence of residual or recurrent cholesteatoma at revision surgery is matched with preoperative findings on MRI. RESULTS: MRI could correctly detect the residual disease in 54.5% of the surgically matched residual or recurrent cholesteatomas. MRI yielded a false-negative result in 45.5%. There was 1 false-positive result (10%). Sensitivity, specificity, and positive and negative predictive values of MRI were 54.4%, 90%, 92.3%, and 47.4%, respectively. CONCLUSION: Preoperative MRI could correctly detect residual or recurrent cholesteatoma in somewhat over half the cases. A high number of false-negative results were obtained. At thismoment, MRI cannot yet replace revision surgery.
ISSN: 1531-7129
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Research Group Experimental Oto-rhino-laryngology
Translational MRI (+)
× corresponding author
# (joint) last author

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