Title: Synthesis and biological evaluation of inosine phosphonates
Authors: Abramov, Mikhail
Herdewijn, Piet # ×
Issue Date: 2010
Publisher: Royal soc chemistry
Series Title: New journal of chemistry vol:34 issue:5 pages:875-876
Abstract: The 4'-phosphonomethoxy analogs of inosine and 2',3'-dideoxyinosine were synthesized and tested for their activity against HCV and HIV, but found to be inactive. During the course of this synthetic investigation, an unexpected oxidative cleavage of the 2',3'-bond of 2'-deoxyinosine was observed.
ISSN: 1144-0546
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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