Title: The outcome of twin reversed arterial perfusion sequence diagnosed in the first trimester
Authors: Lewi, Liesbeth ×
Valencia, Catalina
Gonzalez, Esperanza
Deprest, Jan
Nicolaides, Kypros H #
Issue Date: 2-Jun-2010
Publisher: Mosby, Inc.
Series Title: American Journal of Obstetrics and Gynecology vol:203 issue:3 pages:213.e1-213.e4
Abstract: OBJECTIVE: The aim of this study was to document the mortality of twin reversed arterial perfusion (TRAP) sequence from the first trimester to planned intervention at 16-18 weeks. STUDY DESIGN: A retrospective review was performed of the outcome of monochorionic twin pregnancies diagnosed with twin reversed arterial perfusion sequence in the first trimester. RESULTS: Twenty-six pregnancies were diagnosed with twin reversed arterial perfusion sequence in the first trimester: 2 opted for termination of pregnancy and 24 opted for prophylactic intervention to arrest the reversed flow, which was planned at 16-18 weeks. In 8 of 24 (33%) pregnancies, spontaneous death of the pump twin occurred between diagnosis and planned intervention. In 5 of 24 (21%), there was a spontaneous arrest of flow; whereas, in 11 (46%) there was persistent flow toward the acardiac twin at 16-18 weeks. CONCLUSION: Twin reversed arterial perfusion carries a high mortality between the first and early second trimester.
ISSN: 0002-9378
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pathophysiology of Pregnancy Section (-)
Section Woman - Miscellaneous (-)
Foetal Medicine Section (-)
× corresponding author
# (joint) last author

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