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Title: The neurobiology of amyotrophic lateral sclerosis
Authors: Abreu Bento, AndrĂ© ×
Van Damme, Philip
Van Den Bosch, Ludo
Robberecht, Wim #
Issue Date: Jun-2010
Publisher: Published on behalf of the European Neuroscience Association by Oxford University Press
Series Title: European Journal of Neuroscience vol:31 issue:12 pages:2247-2265
Abstract: Abstract Amyotrophic lateral sclerosis is a degenerative disease affecting the motor neurons. In spite of our growing insights into its biology, it remains a lethal condition. The identification of the cause of several of the familial forms of ALS allowed generation of models to study this disease both in vitro and in vivo. Here, we summarize what is known about the pathogenic mechanisms of ALS induced by hereditary mutations, and attempt to identify the relevance of these findings for understanding the pathogenic mechanisms of the sporadic form of this disease.
URI: 
ISSN: 0953-816X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Neurobiology (Vesalius Research Center)
Research Group Experimental Neurology
× corresponding author
# (joint) last author

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