Title: Thermodynamic and structural behaviour of equimolar POPC/CnE4 (n=8, 12, 16) mixtures by sorption gravimetry, H-2 NMR spectroscopy and X-ray diffraction
Authors: Pfeiffer, Helge ×
Klose, G.
Heremans, Karel #
Issue Date: Mar-2010
Publisher: Elsevier ireland ltd
Series Title: Chemistry and physics of lipids vol:163 issue:3 pages:318-328
Abstract: The hydration behaviour of equimolar mixtures of phospholipids and nonionic surfactants with different chain length was investigated by gravimetric sorption, NMR spectroscopy and X-ray diffraction. At the most hydration degrees investigated, the incorporation of nonionic surfactants in a phospholipid bilayer leads to an increase of the hydrophilicity, which can be shown by the presence of excess hydration. The increased hydrophilicity could be explained by the excavation of additional water binding sites due to the "dilution" of the dipole field of the phospholipid bilayer. Another related contribution arises from the increase of the accessible surface area due to the increase of gauche conformers that result from the steric mismatch when surfactants are incorporated into the phospholipid matrix. H-2 NMR spectroscopy was used to determine the quadrupolar splitting representing a measure of the order state of water. The swelling behaviour could be assessed by small-angle X-ray diffraction. P-31 NMR spectroscopy was applied for the assignment of phase structures to the respective hydration range. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
ISSN: 0009-3084
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Mechanical Metallurgy Section (-)
Department of Materials Engineering - miscellaneous
Chemistry - miscellaneous
× corresponding author
# (joint) last author

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