Title: The cloning, phylogenetic relationship and distribution pattern of two new putative GPCR-type octopamine receptors in the desert locust (Schistocerca gregaria)
Authors: Verlinden, Heleen ×
Vleugels, Rut
Marchal, Elisabeth
Badisco, Liesbeth
Tobback, Julie
Pflüger, HJ
Blenau, Wolfgang
Vanden Broeck, Jozef #
Issue Date: Aug-2010
Publisher: Pergamon Press
Series Title: Journal of Insect Physiology vol:56 issue:8 pages:868-875
Abstract: The biogenic amine octopamine functions as a neuromodulator, neurotransmitter and neurohormone in
insect nervous systems. It plays a prominent role in modulating multiple physiological and behavioural
processes in invertebrates. Octopamine exerts its effects by binding to specific receptor proteins that
belong to the superfamily of G protein-coupled receptors. We found two partial sequences of putative
octopamine receptors in the desert locust Schistocerca gregaria (SgOctaR and SgOctbR) and investigated
their transcript levels in males and females of both phases and during the transition between long-term
solitarious and gregarious locusts. The transcript levels of SgOctaR are the highest in the central nervous
system, whereas those of SgOctbR are the highest in the flight muscles, followed by the central nervous
system. Both SgOctaR and SgOctbR show higher transcript levels in long-term gregarious locusts as
compared to solitarious ones. The rise of SgOctbR transcript levels already appears during the first 4 h of
gregarisation, during which also the behavioural changes take place.
ISSN: 0022-1910
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Research Group Molecular Developmental Physiology and Signal Transduction (-)
× corresponding author
# (joint) last author

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