Title: Joint modelling of multivariate longitudinal profiles: pitfalls of the random-effects approach
Authors: Fieuws, Steffen ×
Verbeke, Geert #
Issue Date: Oct-2004
Series Title: Statistics in medicine vol:23 issue:20 pages:3093-104
Abstract: Due to its flexibility, the random-effects approach for the joint modelling of multivariate longitudinal profiles received a lot of attention in recent publications. In this approach different mixed models are joined by specifying a common distribution for their random-effects. Parameter estimates of this common distribution can then be used to evaluate the relation between the different responses. Using bivariate longitudinal measurements on pure-tone hearing thresholds, it will be shown that such a random-effects approach can yield misleading results for evaluating this relationship.
ISSN: 0277-6715
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat)
× corresponding author
# (joint) last author

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