Title: Interpreting age-related aspects of antihypertensive treatment: statistical defects and their remedy
Authors: Murray, G D ×
Lesaffre, Emmanuel
Robertson, J I #
Issue Date: Nov-1988
Host Document: Journal of hypertension. Supplement : official journal of the International Society of Hypertension vol:6 issue:1 pages:S121-6
Abstract: Much of the literature concerning age-related effects in hypertension and its treatment suffers from serious deficiencies in statistical design and analysis. The problems include the measurement of response to treatment, the lack of a suitable control group, the way response is related to baseline blood pressure, the interpretation of post hoc analyses and the pooling of data from related but different studies. We discuss these problems and attempt to identify solutions which give a satisfactory balance between scientific validity and the practical issues of conducting clinical trials in hypertension.
ISSN: 0952-1178
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Leuven Biostatistics and Statistical Bioinformatics Centre (L-BioStat)
× corresponding author
# (joint) last author

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