Effect of fluvastatin on long-term outcome after coronary revascularization with stent implantation
Saia, Francesco × de Feyter, Pim Serruys, Patrick W Lemos, Pedro A Arampatzis, Chourmouzios A Hendrickx, Guy R Delarche, Nicholas Goedhart, Dick Lesaffre, Emmanuel Branzi, Angelo #
The American journal of cardiology vol:93 issue:1 pages:92-5
We assessed the impact of long-term fluvastatin treatment on adverse atherosclerotic cardiac events (cardiac death, myocardial infarction, and revascularization excluding repeat interventions due to restenosis in the first 6 months) in 847 patients (fluvastatin [n = 417] or placebo [n = 430]) with average cholesterol levels treated with stents in the Lescol Intervention Prevention Study (LIPS). During the 4-year follow-up period, fluvastatin significantly decreased total cholesterol and low-density lipoprotein cholesterol levels and decreased the risk of first adverse atherosclerotic cardiac events by 30% compared with placebo (95% confidence interval -49 to -3.4, p = 0.03).