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Title: Association of headache with childhood adversity and mental disorder: cross-national study
Authors: Lee, Sing ×
Tsang, Adley
Von Korff, Michael
de Graaf, Ron
Benjet, Corina
Haro, Josep Maria
Angermeyer, Matthias
Demyttenaere, Koen
de Girolamo, Giovanni
Gasquet, Isabelle
Merikangas, Kathleen
Posada-Villa, José
Takeshima, Tadashi
Kessler, Ronald C #
Issue Date: Feb-2009
Publisher: Royal Medico-Psychological Association
Series Title: British Journal of Psychiatry vol:194 issue:2 pages:111-116
Abstract: BACKGROUND: Community studies about the association of headache with both childhood family adversities and depression/anxiety disorders are limited. AIMS: To assess the independent and joint associations of childhood family adversities and early-onset depression and anxiety disorders with risks of adult-onset headache. METHOD: Data were pooled from cross-sectional community surveys conducted in ten Latin and North American, European and Asian countries (n=18 303) by using standardised instruments. Headache and a range of childhood family adversities were assessed by self-report. RESULTS: The number of childhood family adversities was associated with adult-onset headache after adjusting for gender, age, country and early-onset depression/anxiety disorder status (for one adversity, hazard ratio (HR)=1.22-1.6; for two adversities, HR=1.19-1.67; for three or more adversities, HR=1.37-1.95). Early and current onset of depression/anxiety disorders were independently associated (HR=1.42-1.89) with adult-onset headache after controlling for number of childhood family adversities. CONCLUSIONS: The findings call for a broad developmental perspective concerning risk factors for development of headache.
URI: 
ISSN: 0007-1250
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Psychiatry
× corresponding author
# (joint) last author

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