Title: Cell therapy strategies and improvements for muscular dystrophy
Authors: Quattrocelli, Mattia ×
Cassano, Marco
Crippa, Stefania
Perini, Ilaria
Sampaolesi, Maurilio #
Issue Date: Aug-2010
Publisher: E. Arnold
Series Title: Cell Death and Differentiation vol:17 issue:8 pages:1222-1229
Abstract: Understanding stem cell commitment and differentiation is a critical step towards clinical translation of cell therapies. In past few years, several cell types have been characterized and transplanted in animal models for different diseased tissues, eligible for a cell-mediated regeneration. Skeletal muscle damage is a challenge for cell- and gene-based therapeutical approaches, given the unique architecture of the tissue and the clinical relevance of acute damages or dystrophies. In this review, we will consider the regenerative potential of embryonic and somatic stem cells and the outcomes achieved on their transplantation into animal models for muscular dystrophy or acute muscle impairment.Cell Death and Differentiation advance online publication, 30 October 2009; doi:10.1038/cdd.2009.160.
ISSN: 1350-9047
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Interdepartemental Stem Cell Institute (-)
Hematology Section (-)
× corresponding author
# (joint) last author

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