Title: A physical map of the chicken genome
Authors: Wallis, John W ×
Aerts, Jan
Groenen, Martien A M
Crooijmans, Richard P M A
Layman, Dan
Graves, Tina A
Scheer, Debra E
Kremitzki, Colin
Fedele, Mary J
Mudd, Nancy K
Cardenas, Marco
Higginbotham, Jamey
Carter, Jason
McGrane, Rebecca
Gaige, Tony
Mead, Kelly
Walker, Jason
Albracht, Derek
Davito, Jonathan
Yang, Shiaw-Pyng
Leong, Shin
Chinwalla, Asif
Sekhon, Mandeep
Wylie, Kristine
Dodgson, Jerry
Romanov, Michael N
Cheng, Hans
de Jong, Pieter J
Osoegawa, Kazutoyo
Nefedov, Mikhail
Zhang, Hongbin
McPherson, John D
Krzywinski, Martin
Hillier, Ladeana
Mardis, Elaine R
Wilson, Richard K
Warren, Wesley C #
Issue Date: 9-Nov-2004
Publisher: Nature Publishing Group
Series Title: Nature vol:432 issue:7018 pages:761-764
Abstract: Strategies for assembling large, complex genomes have evolved to include a combination of whole-genome shotgun sequencing and hierarchal map-assisted sequencing. Whole-genome maps of all types can aid genome assemblies, generally starting with low-resolution cytogenetic maps and ending with the highest resolution of sequence. Fingerprint clone maps are based upon complete restriction enzyme digests of clones representative of the target genome, and ultimately comprise a near-contiguous path of clones across the genome. Such clone-based maps are used to validate sequence assembly order, supply long-range linking information for assembled sequences, anchor sequences to the genetic map and provide templates for closing gaps. Fingerprint maps are also a critical resource for subsequent functional genomic studies, because they provide a redundant and ordered sampling of the genome with clones. In an accompanying paper we describe the draft genome sequence of the chicken, Gallus gallus, the first species sequenced that is both a model organism and a global food source. Here we present a clone-based physical map of the chicken genome at 20-fold coverage, containing 260 contigs of overlapping clones. This map represents approximately 91% of the chicken genome and enables identification of chicken clones aligned to positions in other sequenced genomes.
ISSN: 0028-0836
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
× corresponding author
# (joint) last author

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