Title: The spectrum of adult congenital heart disease in Europe: morbidity and mortality in a 5 year follow-up period. The Euro Heart Survey on adult congenital heart disease
Authors: Engelfriet, Peter ×
Boersma, Eric
Oechslin, Erwin
Tijssen, Jan
Gatzoulis, Michael A
Thilén, Ulf
Kaemmerer, Harald
Moons, Philip
Meijboom, Folkert
Popelová, Jana
Laforest, Valérie
Hirsch, Rafael
Daliento, Luciano
Thaulow, Erik
Mulder, Barbara #
Issue Date: Nov-2005
Series Title: European heart journal vol:26 issue:21 pages:2325-33
Abstract: AIMS: To describe clinical and demographic characteristics at baseline of a European cohort of adults with congenital heart disease (CHD) and to assess mortality and morbidity in a 5 year follow-up period. METHODS AND RESULTS: Data collected as part of the Euro Heart Survey on adult CHD was analysed. This entailed information transcribed from the files of 4110 patients diagnosed with one of eight congenital heart conditions ('defects'), who consecutively visited the outpatient clinics of one of the participating centres in 1998. The patients were included retrospectively and followed until the end of 2003 for a median follow-up of 5.1 years. Notwithstanding their overall relatively good functional class and low mortality over the follow-up period, a considerable proportion of the patients had a history of endocarditis, arrhythmias, or vascular events. There were major differences between the eight defects, both in morbidity and regarding specific characteristics. Outcomes were worst in cyanotic defects and in the Fontan circulation, but a considerable proportion of the other patients also suffer from cardiac symptoms. In particular, arrhythmias are common. CONCLUSION: The spectrum of adult CHD in Europe emerging from this survey is one of a predominantly young population with substantial morbidity but relatively low mortality in a 5 year period.
ISSN: 0195-668X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Academic Centre for Nursing and Midwifery
× corresponding author
# (joint) last author

Files in This Item:
File Description Status SizeFormat
Engelfriet Eur Heart J 2005 vol26 p2325-2333.pdf Published 121KbAdobe PDFView/Open Request a copy

These files are only available to some KU Leuven Association staff members


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science