Title: A Brown Tumor after Biliopancreatic Diversion for Severe Obesity (vol 56, pg 263, 2009)
Authors: Benhalima, Katrien
Mertens, Ann
Van den Bruel, Annick
Laga, Katrien
Vanderschueren, Dirk
Samson, Ignace
Van Damme, Boudewijn
Bouillon, Roger
Issue Date: Jun-2009
Publisher: Japan endocrine soc
Series Title: Endocrine journal vol:56 issue:3 pages:534-534
Abstract: A case of a brown tumor due to iatrogenic malabsorption following biliopancreatic diversion (BPD) is presented. A 52 year old women with a history of BPD 2 years before was referred to orthopedic surgery because of a painful lytic lesion of the left ankle. A bone biopsy revealed a giant cell tumor compatible with the diagnosis of a brown tumor. Subsequent metabolic evaluation showed severe 25-hydroxy vitamin D deficiency and secondary hyperparathyroidism (PTH 60 ng/L or twice the upper normal limit). Bone mineral density was decreased at the femoral neck (0.50 g/cm2; T score of ―3.92 or 66% of the expected value) and lumbar spine (T score of ―1.75 or 93% of the expected value). A brown tumor can be the presenting symptom of iatrogenic malabsorption due to BPD. This case illustrates the severity of potential bone complications after BPD and the necessity of lifelong surveillance and vitamin supplements after BPD.
ISSN: 0918-8959
Publication status: published
KU Leuven publication type: DI
Appears in Collections:Orthopaedics Section (-)
Clinical and Experimental Endocrinology
Translational Cell & Tissue Research

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