Title: Reply to Juan Morote's Letter to the Editor re: Felix K. Chun, Alexandre de la Taille, Hendrik van Poppel, et al. Prostate Cancer Gene 3 (PCA3): Development and Internal Validation of a Novel Biopsy Nomogram. Eur Urol 2009;56:659-68
Other Titles: Letter to the Editor
Authors: Chun, Felix K ×
de la Taille, Alexandre
Van Poppel, Hendrik
Marberger, Michael
Stenzl, Arnulf
Mulders, Peter F A
Huland, Hartwig
Abbou, Clement-Claude
Stillebroer, Alexander B
van Gils, Martijn P M Q
Schalken, Jack A
Fradet, Yves
Marks, Leonard S
Ellis, William
Partin, Alan W
Haese, Alexander #
Issue Date: Jan-2010
Publisher: Elsevier Science
Series Title: European Urology vol:57 issue:1 pages:E2-E3
Abstract: Our paper investigated prostate cancer gene 3 (PCA3) in the largest reported cohort to date of men at risk of prostate cancer (PCa) (n = 809) [1]. All patients from two prospective, multicenter studies from Europe and North America, were subjected to ≥10 cores at either initial or repeat prostate biopsy. We clearly demonstrate that the urinary marker PCA3 represents a novel, informative PCa detection marker. Furthermore, we report the first internally validated PCA3-based nomograms that accurately identify individuals at risk of harboring PCa. Thus, if a PCA3 score is available in combination with established risk factors, these novel nomograms assist clinicians in deciding whether further prostatic evaluation is necessary.
ISSN: 0302-2838
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Urology Section (-)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science