Title: Bioactive glass coating for hard and soft tissue bonding on Ti6Al4V and silicone rubber using electron beam ablation
Authors: Schrooten, Jan ×
Jaecques, Siegfried
Eloy, Rosy
Delubac, Claire
Schultheiss, Christoph
Brenner, Patrice
Buth, Lothar H.O.
Van Humbeeck, Jan
Vander Sloten, Jozef #
Issue Date: 2004
Publisher: Trans Tech Publications
Series Title: Key Engineering Materials vol:254-256 pages:427-430
Abstract: The adhesion of soft tissue to any commonly used implant material is poor. Therefore percutaneous implants are an infectious passage of bacteria into the body. To address this problem, a method that allows the growth of living soft tissue on medical implants ranging from metals to temperature sensitive polymers is developed. The implant surface is to be coated with bioactive glass (BAG) by applying electron beam ablation (ELBA). A proof of principle of the ELBA potential is given by coating Ti6Al4V and silicone rubber (poly-dimethylsiloxane, PDMS) substrates with thin BAG layers (similar to10 mum thickness). The BAG coatings are amorphous, sufficiently adherent and showed the desired bioactive in vitro dissolution behaviour in Hanks' solution. Finally, in vitro fibroblast cell adhesion experiments were performed. Compared to an uncoated material both the coated PDMS and Ti6Al4V samples showed good cell adhesion and proliferation. These results support the hypothesis that a BAG coating deposited by ELBA can enhance the tissue bonding potential of many types of implants, including those made of temperature sensitive materials.
ISSN: 1013-9826
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Materials Engineering - miscellaneous
Biomechanics Section
Biomaterials - BIOMAT
Physical Metallurgy and Materials Engineering Section (-)
× corresponding author
# (joint) last author

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