The adhesion of soft tissue to any commonly used implant material is poor. Therefore percutaneous implants are an infectious passage of bacteria into the body. To address this problem, a method that allows the growth of living soft tissue on medical implants ranging from metals to temperature sensitive polymers is developed. The implant surface is to be coated with bioactive glass (BAG) by applying electron beam ablation (ELBA). A proof of principle of the ELBA potential is given by coating Ti6Al4V and silicone rubber (poly-dimethylsiloxane, PDMS) substrates with thin BAG layers (similar to10 mum thickness). The BAG coatings are amorphous, sufficiently adherent and showed the desired bioactive in vitro dissolution behaviour in Hanks' solution. Finally, in vitro fibroblast cell adhesion experiments were performed. Compared to an uncoated material both the coated PDMS and Ti6Al4V samples showed good cell adhesion and proliferation. These results support the hypothesis that a BAG coating deposited by ELBA can enhance the tissue bonding potential of many types of implants, including those made of temperature sensitive materials.