Title: Caries-related salivary microorganisms and salivary flow rate in bone marrow recipients
Authors: Dens, F ×
Boogaerts, Marc
Boute, P
Declerck, Dominique
Demuynck, H
Vinckier, Frans
Belgium, B #
Issue Date: Jan-1996
Publisher: Elsevier BV
Series Title: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology vol:81 issue:1 pages:38-43
Abstract: Cancer treatments often induce oral complications. In this study we investigate longitudinally the salivary gland function, the salivary caries-related microorganisms, and buffer capacity in bone marrow recipients. Stimulated saliva samples were taken midmorning. The salivary factors were studied in 42 patients from before transplant until 4 months after transplant. A dramatic reduction (66%) of salivary flow rate is noticed in all patients at 1 month after transplant, and only a partial recovery (42% reduction) is seen after 4 months. A clear shift toward a lower buffer capacity and a higher amount of cariogenic microorganisms is seen posttransplant. This shift is more pronounced when total body irradiation was included in the pretransplant conditioning therapy. These findings indicate that the studied parameters in transplant recipients can contribute to a higher caries risk and oral complications during the early posttransplant period.
ISSN: 2212-4403
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biomaterials - BIOMAT
Hematology Section (-)
× corresponding author
# (joint) last author

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