Title: Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial
Authors: Topol, CE ×
Califf, RM
Simes, RJ
Van de Werf, Frans
Diaz, R
Paolasso, E
Aylward, PE
Keech, A
Klein, W
Piegas, L
Tomov, I
Armstrong, PW
Widimsky, P
Grande, P
Halinen, M
Vahanian, A
Neuhaus, K
Dimas, AP
Preda, I
Kristinsson, A
Tzivoni, D
Ardissino, D
White, HD
Madsen, S
Sugrue, D
Sadowski, Z
Seabra-Gomes, R
Apetrei, E
Dalby, A
Betriu, A
Pfisterer, M
Verheugt, F
Fox, K
Bates, ER
Gibler, WB
Granger, CB
Harrington, RA
Hochman, JS
Holmes, DR
Kleiman, NS
Lee, KL
Moliterno, DJ
Newby, LK
Ohman, EM
Califf, R
Newby, K
Zillman, L
Lee, K
Lemons, P
McCourt, B
Campbell, C
Tardiff, B
Snapp, J
Bassett, K
Hodgson, P
Hannan, K
Kandzari, L
Hawkins, S
Hinman-Smith, E
McDougal, M
Raffetto, K
Thompson, D
Wehrle, T
Ange, C
Brown, R
Grissom, G
Heuckel, M
McCall, J
Pennachi, W
Spychala, M
Veasey, S
Pullium, M
Journey, T
Quintero, K
Mark, D
Davidson-Ray, L
Diner, L
Nelson, C
Sowers, C
Webb, G
Young, M
Bhapkar, M
Pacchiana, C
Sparapani, R
Tuttle, R
Weaver, D
Borzak, S
Douthat, L
Topol, E
Moliterno, D
Konczos, L
Baishnab, R
Baishnab, R
Bakos, A
Blashford, L
Bratsch, J
Brown, K
Cadorini, E
Carlson, J
Clemmons, P
DelValle, M
Drabik, M
Fu, G
Gates, K
Gibson, Y
Heil, L
Hill, N
Klancar, R
McHale, B
Montague, E
Pasca, N
Pergi, L
Randall, R
Rosso, R
Sankovich, K
Smith, D
Wisniewski, L
Witkowski, M
Zovkic, V
Alexander, K
Bhatt, D
Brener, S
Campbell, L
Cho, L
Cole, C
Deedy, M
Foody, J
Gassler, J
Ghaffari, S
Haas, G
Kapadia, S
Lauer, M
Lauer, MS
Lincoff, M
Lutton, S
Marso, S
Mukherjee, D
Patel, V
Penn, M
Robbins, M
Roe, M
Sila, C
Thamilarasan, M
Wagner, G
Armstrong, P
Bestilny, S
Van de Werf, Frans
Budts, Werner
Graux, S
Luyten, Anne
Simes, J
Keech, A
Kava, M
Bower, T
Chan, S
Crampton, L
Monro, C
Nayak, M
Parente, G
Riley, V
Wilton, D
Aylward, P
Dolan, S
Thomas, C
White, H
Scott, M
Frye, R
Alpert, J
Bertrand, M
Ryan, T
Fisher, L
Asarch, L
Smith, M
Lim, L
Bokslag, M
Chiu, P
Chung, J
Collins, S
Dougherty, C
Guimaraes, D
Hakim, Z
Mathieson, J
Montgomery, L
Novotny, B
Steiner, B
Wittke, B #
Issue Date: Jan-2000
Publisher: Lancet ltd
Series Title: Lancet vol:355 issue:9201 pages:337-345
Abstract: Background Aspirin lowers risks of death and myocardial infarction in patients with acute coronary syndromes. Intravenous glycoprotein IIIb/IIIa receptor antagonists further reduce the rates of ischaemic events in these patients, but the efficacy of long-term oral glycoprotein IIb/IIIa receptor blockade has not been established. We tested whether the oral glycoprotein IIb/IIIa receptor antagonist sibrafiban would prevent more cardiovascular events than aspirin, when given within 7 days of, and sustained for 90 days after, an acute coronary syndrome event.
ISSN: 0140-6736
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cardiology
× corresponding author
# (joint) last author

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