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Title: Nicotinic acetylcholine receptor blocking effect of guanethidine in the rat gastric fundus
Authors: Blommaart, PJE ×
Ferwerda, G
Kodde, A
Tytgat, GNJ
Boeckxstaens, Guy #
Issue Date: Oct-1999
Publisher: Stockton press
Series Title: British journal of pharmacology vol:128 issue:4 pages:903-908
Abstract: 1 Guanethidine is commonly used as a drug to investigate adrenergic neurotransmission and, in combination with atropine, to realize non-adrenergic non-cholinergic (NANC) conditions. Previous studies suggested a nicotinic acetylcholine receptor blocking effect of guanethidine. Therefore, we investigated the effect of increasing concentrations of guanethidine (0.1-100 mu M) on nicotine-induced relaxations of longitudinal muscle strips of rat gastric fundus.
ISSN: 0007-1188
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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