Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice
De Jonge, WJ × The, FO Van Der Coelen, D Bennink, RJ Reitsma, PH Van Deventer, SJ Van Den Wijngaard, RM Boeckxstaens, Guy #
W b saunders co
Gastroenterology vol:127 issue:2 pages:535-545
Background & Aims: Inflammation of the intestinal muscularis following manipulation during surgery plays a crucial role in the pathogenesis of postoperative ileus. Here, we evaluate the role of mast cell activation in the recruitment of infiltrates in a murine model.