Interstitial cells of Cajal are involved in the afferent limb of the rectoanal inhibitory reflex
de Lorijn, F × de Jonge, WJ Wedel, T Vanderwinden, JM Benninga, MA Boeckxstaens, Guy #
B m j publishing group
Gut vol:54 issue:8 pages:1107-1113
Background and aims: Interstitial cells of Cajal (ICC) have been shown to be involved in nitrergic neurotransmission of the lower oesophageal sphincter and pylorus. Here we studied the role of ICC and nitric oxide ( NO) in the inhibitory neurotransmission of the murine internal anal sphincter (IAS).