Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus
The, F. O × Bennink, R. J Ankum, W. M Buist, M. R Busch, O. R. C Gouma, D. J Van der Heide, S van den Wijngaard, R. M de Jonge, W. J Boeckxstaens, Guy #
B m j publishing group
Gut vol:57 issue:1 pages:33-40
Background: Murine postoperative ileus results from intestinal inflammation triggered by manipulation-induced mast cell activation. As its extent depends on the degree of handling and subsequent inflammation, it is hypothesised that the faster recovery after minimal invasive surgery results from decreased mast cell activation and impaired intestinal inflammation.