Title: Click chemistry under non-classical reaction conditions
Authors: Kappe, C.O. ×
Van der Eycken, Erik #
Issue Date: 2010
Publisher: Royal Society of Chemistry
Series Title: Chemical Society Reviews vol:39 issue:4 pages:1280-1290
Abstract: First described almost a decade ago, "click'' reactions such as the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) are widely used today in organic and medicinal chemistry, in the polymer and material science field, and in chemical biology. While most click reactions can be performed at room temperature there are instances where some form of process intensification is required. In this tutorial review, aimed at the synthetic chemistry community, examples of click chemistry carried out under non-classical reaction conditions, such as for example applying microwave heating or continuous flow processing will be highlighted.
ISSN: 0306-0012
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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