Title: Effect of a lactoperoxidase containing toothpaste in radiation-induced xerostomia
Authors: van Steenberghe, Daniel ×
Van den Eynde, E
Jacobs, Reinhilde
Quirynen, Marc #
Issue Date: Apr-1994
Series Title: International dental journal vol:44 issue:2 pages:133-8
Abstract: Fractioned irradiation of the oral region may cause xerostomia and an increased infection risk. The aim of this study was to evaluate, in a single blind, cross-over trial, the effectiveness of a test toothpaste containing the lactoperoxidase system, compared to a normal fluoridated toothpaste. Twelve patients with pronounced xerostomia were examined during a 52-day period. The following parameters were observed: plaque and gingivitis index, bleeding on probing, probing pocket depth, attachment level, and quality of subgingival plaque (phase contrast microscopy). The test toothpaste reduced the rate of supragingival plaque formation over a longer period. Furthermore, gingival inflammation was lower in the test group. For the other parameters, time-dependent changes were not significant. This pilot-study demonstrates the efficacy of the lactoperoxidase system administered by a toothpaste, on supragingival plaque control in xerostomic patients.
ISSN: 0020-6539
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Periodontology
Oral Imaging
× corresponding author
# (joint) last author

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