The complex refractive index of fluorinated subphthalocyanines (ScbPcs) deposited by vacuum sublimation is determined by spectral ellipsometry. Their performance as acceptor material is characterized in a range of donor/acceptor heterojunctions in organic photovoltaic cells (OPVCs) by current- voltage measurements under 1 sun AM 1.5D simulated solar illumination and spectral response. Both electron and hole transfer between donor and acceptor materials is demonstrated. Power conversion efficiencies of 0.96% are found with an open-circuit bias of 940 mV. Hence, it is shown that fluorinated SubPcs can be considered as an acceptor material in OPVCs with an absorption in the visible comparable to that of well-known metallophthalocyanines.