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Title: [Second-line therapy of idiopathic detrusor overactivity : Sacral neuromodulation and botulinum toxin A.]
Other Titles: Second-line-Therapie der idiopathisch überaktiven Blase
Authors: Amend, B ×
Castro-Diaz, D
Chartier-Kastler, E
De Ridder, Dirk
Everaert, K
Spinelli, M
van Kereebroeck, P
Sievert, K-D #
Issue Date: 2010
Publisher: Springer-Verlag
Series Title: Der Urologe vol:49 issue:2 pages:245-252
Abstract: The syndrome of idiopathic overactive bladder (I-OAB) impairs quality of life for the affected individuals. Conservative treatment options such as antimuscarinics are not always effective, and resulting side effects can lead the patient to stop treatment. In recently years, minimally invasive and reversible sacral neuromodulation and botulinum toxin A have become available. Currently, the approved treatment option for I-OAB that is recommended by the International Consultation on Incontinence is sacral neuromodulation by InterStim therapy. This article gives an overview of the present clinical evidence on the effectiveness and reliability of these two treatment modalities as well as the current significance of sacral neuromodulation and botulinum toxin A for the second-line treatment of adult I-OAB.

Der Einsatz von Antimuskarinika in der Behandlung der idiopathisch überaktiven Blase (I-OAB) stößt aufgrund von fehlender Wirksamkeit und Nebenwirkungen oft an seine Grenzen. In der Vergangenheit stellten invasive chirurgische Verfahren die notwendige Konsequenz bei Versagen der medikamentösen Therapie dar. Mit der evidenzbasierten sakralen Neuromodulation und der aktuell noch nicht zugelassenen Therapie mit Botulinumtoxin A stehen dem behandelnden Urologen neue, minimal-invasive
Therapieverfahren zur Verfügung.
Eine Beurteilung des Einsatzes dieser Methoden gibt der nachfolgende Artikel.
ISSN: 0340-2592
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Urology Section (-)
× corresponding author
# (joint) last author

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