Title: Pemetrexed plus cisplatin or pemetrexed plus carboplatin for chemonaive patients with malignant pleural mesothelioma: Results of the International Expanded Access Program
Authors: Santoro, Armando ×
O'Brien, Mary E
Stahel, Rolf A
Nackaerts, Kristiaan
Baas, Paul
Karthaus, Meinolf
Eberhardt, Wilfried
Paz-Ares, Luis
Sundstrom, Stein
Liu, Yushan
Ripoche, Veronique
Blatter, Johannes
Visseren-Grul, Carla M
Manegold, Christian #
Issue Date: Jul-2008
Publisher: Lippincott Williams & Wilkins
Series Title: Journal of Thoracic Oncology vol:3 issue:7 pages:756-763
Abstract: Introduction: Previously published results from a randomized phase III study of pemetrexed plus cisplatin in patients with malignant pleural mesothelioma (MPM) demonstrated a significant survival benefit and higher response rate compared with cisplatin. Although pernetrexed was under review by regulatory agencies, an International Expanded Access Program (EAP) provided more than 3000 mesothelioma patients with access to single-agent pemetrexed or pernetrexed in combination with cisplatin or carboplatin in 13 countries. This manuscript reports the safety and efficacy data from the nonrandomized open-label study in chemonaive patients receiving pernetrexed plus platinum under the EAP.
ISSN: 1556-0864
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pneumology
× corresponding author
# (joint) last author

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