Title: Microwave-assisted synthesis of substituted 2-amino-1H-imidazoles from imidazo[1,2-a]pyrimidines
Authors: Ermolat'ev, D. S ×
Svidritsky, E. P
Babaev, E. V
Van der Eycken, Erik #
Issue Date: Sep-2009
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:50 issue:37 pages:5218-5220
Abstract: An efficient method for the synthesis of mono- and disubstituted 2-amino-1H-imidazoles via microwave-assisted hydrazinolysis of substituted imidazo[1,2-a]pyrimidines is reported. This protocol avoids strong acidic conditions and is superior to the classical cyclocondensation of alpha-haloketones with N-acetylguanidine. (C) 2009 Elsevier Ltd. All rights reserved.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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