Title: Type 1 diabetes: entering the proteomic era
Authors: D'Hertog, Wannes
Mathieu, Chantal
Overbergh, Lutgart # ×
Issue Date: 5-Apr-2006
Publisher: Future Drugs Ltd.
Series Title: Expert Review of Proteomics vol:3 issue:2 pages:223-236
Abstract: During the last decade, a major breakthrough in the field of proteomics has been achieved. This review describes available techniques for proteomic analyses, both gel and non-gel based, particularly concentrating on relative quantification techniques. The principle of the different techniques is discussed, highlighting the advantages and drawbacks of recently available visualization methods in gel-based assays. In addition, recent developments for quantitative analysis in non-gel-based approaches are summarized. This review focuses on applications in Type 1 diabetes. These mainly include proteomic studies on pancreatic islets in animal models and in the human situation. Also discussed are mass spectrometry-based studies on T-cells, and studies on the development of diagnostic markers for diabetic nephropathology by capillary electrophoresis coupled to mass spectrometry.
ISSN: 1478-9450
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
Medical Clerkships Centers
× corresponding author
# (joint) last author

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