Title: Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension
Authors: Rex, Steffen ×
Missant, Carlo
Claus, Piet
Buhre, Wolfgang
Wouters, Patrick F #
Issue Date: 2008
Publisher: Biomed central ltd
Series Title: Critical care vol:12 issue:5 pages:1-13
Article number: R113
Abstract: Introduction Prostacyclin inhalation is increasingly used to treat acute pulmonary hypertension and right ventricular failure, although its pharmacodynamic properties remain controversial. Prostacyclins not only affect vasomotor tone but may also have cAMP-mediated positive inotropic effects and modulate autonomic nervous system tone. We studied the role of these different mechanisms in the overall haemodynamic effects produced by iloprost inhalation in an experimental model of acute pulmonary hypertension.
ISSN: 1466-609X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cardiovascular Imaging and Dynamics
Anesthesiology and Algology
× corresponding author
# (joint) last author

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