Background: Decreased renal function appears to be an independent risk factor for overall mortality and particularly for cardiovascular mortality. Only a small proportion of patients will evolve towards end-stage renal failure. Recent research shows kidney function evolution being influenced positively by in time starting appropriate treatment.
Questions: What is the prevalence of chronic kidney disease in general practice in Flanders and has this prevalence previously been under- or overestimated?
Methods: We retrospectively collected data from the Intego database of all patients with a known weight, serum-creatinine, age and gender. We searched if patients were registered or not with the diagnosis of chronic kindney disease. We also estimated the level of GFR by using the MDRD foremula and then calculated the prevelence of decreased renal function in relation to age and gender by using the five stages form the American National Kidney Foundation Guidelines.
Results: Required data were known from 10426 paients. After exclusion of patients younger than 20n years 9969 patients were enrolled of which 5442 woman and 4527 men. The prevalence of stage three or higher stage kindey disease was 16% for woman, 10% for men and 13% for the total population. Prevalence increased with age (2% for patients between 20-39 years and 46% for patienst 80 years and older). Of all those patients only 100 women (1,84%) and 134 men (2,96%) have previously been registered with the diagnosis of kidney disease.
Conclusion: A considerable proportion of the study population seem to have decreased renal function. prevalence is higer in women and increases with age. Only a small proportion of patients uffering form chronic kidney disease had previously been recognised as such in general practice in Flanders.