Title: Anti-CD20 monoclonal antibody (Rituximab) treatment for hepatitis c-negative therapy-resistant essential mixed cryoglobulinemia with renal and cardiac failure
Authors: Ghijsels, Erik ×
Lerut, Evelyne
Vanrenterghem, Yves
Kuypers, Dirk #
Issue Date: May-2004
Publisher: W.B. Saunders
Series Title: American Journal of Kidney Diseases vol:43 issue:5 pages:E34-E38
Abstract: A case of hepatitis C virus (HCV)-negative essential mixed cryoglobulinemia with initial skin, joint, and liver involvement, complicated by severe renal and cardiac failure and resistant to corticosteroid therapy, plasmapheresis, chlorambucil, and cyclophosphamide is presented. Treatment with an anti-CD20 monoclonal antibody (rituximab) induced a persistent recovery of renal and cardiac function, disappearance of skin and joint lesions, and disappearance of cryoglobulins. In a 24-month follow-up period, our patient remains in remission and free of symptoms.
ISSN: 0272-6386
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Laboratory of Nephrology
× corresponding author
# (joint) last author

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