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Title: Importance of HLA-DR matching in polytransfused cadaveric kidney transplant recipients. A prospective one-center study
Authors: Vanrenterghem, Yves ×
Vandeputte, I
Lerut, Antoon
Roels, L
Gruwez, Jacques
Michielsen, Paul #
Issue Date: Nov-1983
Publisher: Williams & wilkins
Series Title: Transplantation vol:36 issue:4 pages:384-387
Abstract: Since August 1978 prospective HLA-DR typing has been performed in 157 donor-recipient pairs. All recipients received pretransplant blood transfusions. This study shows that HLA-DR matching can significantly improve the survival of cadaveric kidney allografts, even in polytransfused recipients. Patients receiving kidneys with no HLA-DR incompatibilities have a one-year graft survival of 97%, versus 86% for recipients with 1 HLA-DR incompatibility and 73% for recipients with 2 HLA-DR incompatibilities. The cumulative dose of corticosteroids during the first year after transplantation is significantly lower in patients with no DR-incompatibilities. HLA-A and B matching have no additional effect on graft survival.
ISSN: 0041-1337
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Thoracic Surgery
Laboratory of Nephrology
× corresponding author
# (joint) last author

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