Title: Tumor necrosis factor receptor gene polymorphisms in Crohn's disease: Association with clinical phenotypes
Authors: Waschke, KA ×
Villani, AC
Vermeire, Severine
Dufresne, L
Chen, TC
Bitton, A
Cohen, A
Thomson, ABR
Wild, GE #
Issue Date: May-2005
Publisher: Nature Publishing Group
Series Title: American Journal of Gastroenterology vol:100 issue:5 pages:1126-1133
Abstract: OBJECTIVES: Crohn's disease (CD) is a chronic multifactorial disorder with diverse clinical features that are influenced by a heterogeneous set of genetic factors. TNF-alpha/TNF receptor interactions play a pivotal role in the pathogenesis of the inflammatory response. Our purpose was to determine whether single nucleotide polymorphisms (SNPs) in the TNF receptors confer susceptibility to Crohn's disease and whether they are associated with clinical phenotype.
ISSN: 0002-9270
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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