Title: Immunogenicity of infliximab : how to handle the problem ?
Authors: Baert, Filip ×
De Vos, Martine
Louis, Edouard
Vermeire, Severine #
Issue Date: Apr-2007
Publisher: Acta Medica Belgica
Series Title: Acta Gastro-Enterologica Belgica vol:70 issue:2 pages:163-170
Abstract: Background: The introduction of infliximab has greatly advanced the therapeutic armamentarium of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Although the benefit/risk ratio for infliximab is positive, of particular concern has been the problem of immunogenicity ascribed to the chimeric properties of the drug. Antibody formation is associated with allergic reactions and loss of response.
ISSN: 0001-5644
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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