Title: Reconstruction of atrioventricular valves with photo-oxidized bovine pericardium
Authors: Verbrugghe, Peter ×
Meuris, Bart
Flameng, Willem
Herijgers, Paul #
Issue Date: Aug-2009
Publisher: Elsevier Science
Series Title: Interactive Cardiovascular and Thoracic Surgery vol:9 issue:5 pages:775-779
Abstract: Repair of complex valve pathological processes often requires the use of leaflet tissue or pericardium. The use of bovine photo-oxidized pericardium may be an alternative, a tissue less prone to calcification. The aim of this study is to evaluate the use of photo-oxidized bovine pericardial tissue in the reconstruction of atrioventricular valves in humans. Between July 2001 and September 2006, 21 patients with complex valve pathology underwent a reconstruction with photo-oxidized pericardium. The pericardial patch was used for the reconstruction of a tricuspid valve leaflet in 2 patients, the reconstruction of a mitral valve leaflet in 6 patients, the reconstruction of the tricuspid annulus in 1 patient and the reconstruction of the mitral annulus in 12 patients. The follow-up ranged from 13.9 to 43.2 months. There were 5 perioperative deaths. Four patients developed failure of the reconstruction, in 1 patient there was thinning and perforation of the pericardial patch without signs of infection or abrasion. The other patients were free from thromboembolism, endocarditis, hemorrhagic complications or echocardiographic signs of failure of the reconstruction. Photo-oxidized bovine pericardium is a versatile material for complex reconstruction of the atrioventricular valvular structures. Its durability should however be investigated in comparison with alternative tissues in a randomized trial. Keywords: Heart valve; Reconstruction; Photo-oxidation; Pericardium.
ISSN: 1569-9293
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Experimental Cardiac Surgery
Clinical Cardiac Surgery
× corresponding author
# (joint) last author

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