Title: G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway
Authors: D'Aniello, Cristina
Lonardo, Enza
Iaconis, Salvatore
Guardiola, Ombretta
Liguoro, Anna Maria
Liguori, Giovanna L
Autiero, Monica
Carmeliet, Peter
Minchiotti, Gabriella # ×
Issue Date: Jul-2009
Publisher: Lippincott williams & wilkins
Series Title: Circulation research vol:105 issue:3 pages:231-U65
Abstract: Rationale: Pluripotent stem cells represent a powerful model system to study the early steps of cardiac specification for which the molecular control is largely unknown. The EGF-CFC (epidermal growth factor-Cripto/FRL-1/Cryptic) Cripto protein is essential for cardiac myogenesis in embryonic stem cells (ESCs).
ISSN: 0009-7330
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Vesalius Research Centre (-)
Laboratory of Angiogenesis and Vascular Metabolism (Vesalius Research Center) (+)
× corresponding author
# (joint) last author

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