Title: Development and evaluation of multiplex Y-STR assays for application in molecular genealogy
Authors: Jacobs, Manon
Janssen, Lynn
Vanderheyden, Nancy
Bekaert, Bram
Van de Voorde, Wim
Decorte, Ronny # ×
Issue Date: 2009
Publisher: Elsevier
Host Document: Forensic Science International. Genetics Supplement Series vol:2 pages:57-59
Conference: 23rd World Congress of the International Society for Forensic Genetics location:Buenos Aires (Argentina) date:15-18 September 2009
Abstract: Three multiplex PCRs were developed for the analysis of 14 single-copy and 4 multi-copy Y chromosome Short Tandem Repeat (STR) loci routinely used by several public genealogical databases. These assays were used in addition to PowerPlex® Y for the analysis of 245 DNA samples from a genealogical project. In total 244 different haplotypes composed of 37 to 40 alleles were identified with one haplotype identical between two males with the same surname. The multi-copy loci DYS464 and DYS724 were the most polymorphic with a gene diversity of at least 0.964. The use of DYS454 and DYS455 can be questioned as these loci had the lowest gene diversity (0.039 and 0.269 respectively).
ISSN: 1875-1768
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Department of Human Genetics - miscellaneous
Forensic Biomedical Sciences
× corresponding author
# (joint) last author

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